105290-99-1

Usage

Uses

Used in Pharmaceutical Research and Drug Discovery:
(1R)-1-(2-METHYLPHENYL)PENTYLAMINE is used as a building block for the synthesis of other compounds, contributing to the development of new pharmaceutical agents.
Used in Central Nervous System Drug Development:
(1R)-1-(2-METHYLPHENYL)PENTYLAMINE may have potential applications in the development of new drugs targeting the central nervous system, due to its unique structure and properties.
Used as a Biochemical Tool:
(1R)-1-(2-METHYLPHENYL)PENTYLAMINE also serves as a biochemical tool for studying the role of amines in biological processes, furthering our understanding of their functions and potential therapeutic applications in various scientific and medical fields.

Upstream product

• 875856-17-0 1-(o-tolyl)pentan-1-imine 
• 109-72-8 n-butyllithium 
• 529-19-1 2-Methylbenzonitrile 
• 542-69-8 1-iodo-butane 

Relevant academic research and scientific papers

Preparation of secondary carbinamines via alkylation of N-boryl imines generated from partial reduction of nitriles with NABH4-carboxylic acid

Secondary carbinamines have been prepared from alkylation of N-boryl imines which were generated in situ from partial reduction of nitriles with sodium borohydride modified by carboxylic acid.

Preparation of Secondary Carbinamines via N-Boryl Imines Generated in situ from Nitriles and Borane-Tetrahydrofuran

N-Boryl imines obtained from partial reduction of nitriles with borane-tetrahydrofuran have been alkylated with organolithium or Grignard reagents to afford secondary carbinamines in moderate to excellent yields.

ENANTIOSELECTIVE SYNTHESIS OF CHIRAL BENZYLIC AMINES. (A STEREOSPECIFIC TRANSAMINATION-ALKYLATION REACTION)

Optically pure arene-chromium-tricarbonyl complex 1 leads to almost optically pure (>95percent ee) benzylic amines in good yields (c.a. 85percent) during a 3-step-reaction involving transfer of a nitrogen atom from a trivial reactant (benzylamine).