1053-58-3 Usage
Uses
Used in Pharmaceutical Industry:
6-alpha-Fluorhydrocortisone is used as an anti-inflammatory agent for treating conditions such as asthma, allergic reactions, and inflammatory disorders. It exerts its therapeutic effects by suppressing the body's immune response and reducing inflammation, thereby alleviating symptoms and improving the quality of life for patients.
Used in Immunosuppressive Therapy:
6-alpha-Fluorhydrocortisone is utilized as an immunosuppressive agent in the management of autoimmune diseases and conditions requiring immune modulation. Its ability to suppress the immune system helps prevent organ rejection in transplant patients and control the progression of autoimmune disorders.
However, the use of 6-alpha-Fluorhydrocortisone should be carefully monitored and administered under the supervision of a healthcare professional to minimize the risk of side effects, such as increased susceptibility to infections, high blood sugar levels, and osteoporosis. Proper dosage and adherence to medical instructions are crucial for ensuring the safe and effective use of this corticosteroid in various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1053-58-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,5 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1053-58:
(6*1)+(5*0)+(4*5)+(3*3)+(2*5)+(1*8)=53
53 % 10 = 3
So 1053-58-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H29FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h7,12-13,15-16,18,23,25,27H,3-6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1
1053-58-3Relevant academic research and scientific papers
Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
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, (2008/06/13)
This invention discloses an improved process for the production of corticoids from 17α-hydroxy steroids utilizing peroxymonosulfate.
Process for preparing 3-enol ethers of 11β-hydroxy-Δ4 -pregnene-3-ones and derivatives thereof
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, (2008/06/13)
3-enol ethers of 11β-hydroxy-Δ4 -pregnene-3-ones are prepared by reacting triethylorthoacetate with an 11β-hydroxy-Δ4 -pregnene-3-one in a solvent which is at least 40% by weight or more ethanol and 60% by weight or less of a compatible oxygenated hydrocarbon liquid in the presence of an acid catalyst. This reaction forms a basis of a process for forming 6-halo-derivatives, particularly 6-chloro-Δ1,4,6 -pregnatrien -11β,17α,21-triol-3,20-dione.
