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(R)-ENDO-CIS-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLIC ACID, commonly known as (R)-baclofen, is a chemical compound with significant therapeutic applications. It functions as a GABA receptor agonist, specifically targeting the GABAB receptors in the central nervous system. This action helps to reduce the activity of excitatory neurotransmitters, leading to a decrease in muscle tone. (R)-ENDO-CIS-2-AZABICYCLO [3,3,0]OCTANE-3-CARBOXYLIC ACID is also under investigation for its potential in treating alcohol dependence and withdrawal symptoms, showcasing its promise in addressing neurological and psychiatric conditions.

105307-53-7

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105307-53-7 Usage

Uses

Used in Pharmaceutical Industry:
(R)-ENDO-CIS-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLIC ACID is used as a muscle relaxant for the treatment of muscle spasticity. Its agonistic effect on GABAB receptors helps to alleviate the symptoms by reducing the hyperactivity of motor neurons, providing relief to patients suffering from conditions like multiple sclerosis or spinal cord injuries.
Used in Neurological Treatments:
(R)-ENDO-CIS-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLIC ACID is utilized as a therapeutic agent in the management of neurological disorders characterized by increased muscle tone. Its ability to modulate neurotransmitter activity makes it a valuable asset in the treatment of such conditions.
Used in Psychiatric Treatments:
(R)-ENDO-CIS-2-AZABICYCLO[3.3,0]OCTANE-3-CARBOXYLIC ACID is being explored for its potential use in treating alcohol dependence and withdrawal symptoms. Its impact on neurotransmitter levels suggests that it may help in reducing cravings and managing the severity of withdrawal symptoms, offering a new approach to addiction treatment.
Used in Research and Development:
(R)-ENDO-CIS-2-AZABICYCLO[3.3.0]OCTANE-3-CARBOXYLIC ACID is employed in scientific research to further understand the role of GABAB receptors in various physiological and pathological processes. Its use in experimental models aids in the development of new therapeutic strategies for a range of neurological and psychiatric conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 105307-53-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,0 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 105307-53:
(8*1)+(7*0)+(6*5)+(5*3)+(4*0)+(3*7)+(2*5)+(1*3)=87
87 % 10 = 7
So 105307-53-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO2/c10-8(11)7-4-5-2-1-3-6(5)9-7/h5-7,9H,1-4H2,(H,10,11)/t5?,6-,7?/m1/s1

105307-53-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-ENDO-CIS-2-AZABICYCLO [3,3,0]OCTANE-3-CARBOXYLIC ACID

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105307-53-7 SDS

105307-53-7Relevant academic research and scientific papers

COUPLING OF β-ACETAMIDO RADICALS WITH α-CHLORO ACRYLONITRILE - A NEW ACCESS TO DISUBSTITUTED PROLINE DERIVATIVES

Henning, R.,Urbach, H.

, p. 5343 - 5346 (2007/10/02)

β-Acetamido radicals are prepared by reduction of organomercurials and coupled with α-chloro-acrylonitrile.The coupling products are further converted to proline derivatives.

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