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5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97, an indole derivative, is a chemical compound with a unique structure featuring a bromoacetyl group and an indol-2-one ring. It is known for its potent inhibitory effect on the enzyme glycogen phosphorylase, which plays a crucial role in the regulation of glucose metabolism. This characteristic makes it a promising candidate for therapeutic applications in diabetes and related metabolic disorders. With a molecular formula of C10H10BrNO2 and a molecular weight of 257.1 g/mol, 5-(BROMOACETYL)-1,3-DIHYDRO-2H-INDOL-2-ONE 97 is relatively small and manageable for synthesis and laboratory research.

105316-98-1

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105316-98-1 Usage

Uses

Used in Pharmaceutical Industry:
5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97 is used as a therapeutic agent for the treatment of diabetes and related metabolic disorders. Its ability to inhibit glycogen phosphorylase makes it a potential candidate for managing glucose levels and improving overall metabolic health.
Used in Research and Development:
In the field of scientific research, 5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97 serves as a valuable tool for studying the role of glycogen phosphorylase in glucose metabolism and its implications in diabetes and other metabolic conditions. Its unique structure and inhibitory properties allow researchers to explore novel approaches to drug development and target identification for metabolic disorders.
Used in Drug Synthesis:
Due to its potent inhibitory effect on glycogen phosphorylase, 5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97 is utilized in the synthesis of new drugs targeting diabetes and metabolic disorders. Its small molecular size and manageable properties make it an attractive starting point for the development of innovative therapeutic agents.
Used in Drug Delivery Systems:
To enhance the bioavailability and therapeutic efficacy of 5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97, it can be incorporated into various drug delivery systems. These systems can improve the compound's stability, solubility, and targeted delivery to specific tissues or organs, thereby optimizing its therapeutic potential.
Used in Biochemical Assays and Screening:
5-(Bromoacetyl)-1,3-dihydro-2H-indol-2-one 97 can be employed in biochemical assays and high-throughput screening processes to identify and evaluate the inhibitory effects of other compounds on glycogen phosphorylase. This can aid in the discovery of new drugs with similar or improved therapeutic properties for the treatment of diabetes and metabolic disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 105316-98-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,1 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105316-98:
(8*1)+(7*0)+(6*5)+(5*3)+(4*1)+(3*6)+(2*9)+(1*8)=101
101 % 10 = 1
So 105316-98-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8BrNO2/c11-5-9(13)6-1-2-8-7(3-6)4-10(14)12-8/h1-3H,4-5H2,(H,12,14)

105316-98-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(2-bromoacetyl)-1,3-dihydroindol-2-one

1.2 Other means of identification

Product number -
Other names 5-bromoacetyloxindole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105316-98-1 SDS

105316-98-1Downstream Products

105316-98-1Relevant academic research and scientific papers

MIF INHIBITORS

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Page/Page column 53-54, (2008/06/13)

The present invention relates to the use of specific benzimidazolone analogues and derivatives to inhibit the cytokine or biological activity of macrophage migration inhibitory factor (MIF), and diseases or conditions wherein MIF cytokine or biological activity is implicated. Novel benzimidazole analogues and derivatives are also provided.

Bicyclic heteroaryl thiazole compounds, cardiotonic compositions including the same, and their uses

-

, (2008/06/13)

Cardiotonic fused aromatic bicyclic ring substituted thiazole compounds and their salts, methods for increasing cardiac contractility in humans and other mammals by the use of said compounds, pharmaceutical compositions including said compounds and methods for compound preparation.

6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses

-

, (2008/06/13)

Cardiotonic fused aromatic bicyclic ring substituted thiazole compounds and their salts, methods for increasing cardiac contractility in humans and other mammals by the use of said compounds, pharmaceutical compositions including said compounds and methods for compound preparation.

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