1053181-40-0Relevant academic research and scientific papers
Synthesis of a metabolite of an anti-angiogenic lead candidate based on a d-glucosamine motif
Singh, Latika,Lam, Ann,Premraj, Rajaratnam,Seifert, Joachim
, p. 4854 - 4856 (2008/09/21)
A rapid synthetic access to ACL 21269 was established in 12 steps starting from thiogylcoside 9 utilizing synthons 8 and 6 to introduce the pharmacophores at positions 1 and 2. The functional groups decorating the glucosamine scaffold were introduced in a particular order and common protecting groups were employed to establish a robust synthetic process.
