1053182-46-9Relevant academic research and scientific papers
New class of β-aminoalcohol ligands derived from isosorbide and isomannide: Application in hydrogen transfer reduction of prochiral ketones
Le, Tin Thanh,Guillarme, Stéphane,Saluzzo, Christine
experimental part, p. 8893 - 8898 (2011/01/04)
Starting from isosorbide and isomannide, two by-products from the starch industry, a family of chiral functionalized β-aminoalcohols presenting a THF ring has been synthesized as potential ligands for hydrogen transfer reduction of prochiral ketones. Unde
New chiral ligands from isosorbide: application in asymmetric transfer hydrogenation
Guillarme, Stephane,Mai Nguyen, Thi Xuan,Saluzzo, Christine
, p. 1449 - 1453 (2008/12/20)
New chiral β-amino alcohols have been designed and synthesized from isosorbide, a by-product from the starch industry. These new ligands have been synthesized in three steps from isosorbide in good yields and have been used in asymmetric transfer hydrogenation reaction with RuII complexes. One of these catalysts also demonstrated good catalytic activity and good enantioselectivity.
