105336-49-0Relevant academic research and scientific papers
Aromatization of enamines promoted by a catalytic amount of Pd/C. Synthesis of aromatic amines
Cossy, Janine,Belotti, Damien
, p. 2557 - 2559 (2002)
(Matrix presented) Aromatic amines were obtained efficiently from enamines by using a catalytic amount of Pd/C in the presence of nitrobenzene and 4 A molecular sieves in refluxing toluene.
Reaction of 4-Bromo-1,2-dimethylbenzene with Various Nucleophiles via Aryne Reaction
Biehl, Edward R.,Razzuk, Aziz,Jovanovic, Misa V.,Khanapure, Subhash P.
, p. 5157 - 5160 (2007/10/02)
4-Bromo-1,2-dimethylbenzene (4a) reacts with a variety of amines, mercaptans, and nitriles under aryne-forming conditions to yield predominantly 4-substituted 1,2-dimethylbenzenes and minor quantities of 3-substituted 1,2-dimethylbenzenes.The product distributions from these reactions are heavily in favor of the 4-substituted isomer since it is formed exclusively from the symmetric 4,5-dimethylbenzyne intermediate (6) and partly from the unsymmetric 3,4-dimethylbenzyne intermediate (5).
