10534-13-1

Usage

Uses

Used in Chemical Synthesis:
CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its high purity and reactivity make it a preferred choice for these applications.
Used in Solvent Applications:
In the chemical industry, CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& is used as a solvent for various processes, such as extraction, purification, and separation. Its ability to dissolve a wide range of substances and its compatibility with different materials make it a versatile solvent.
Used in Research and Development Laboratories:
Due to its high chemical stability and reactivity, CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& is widely used in research and development laboratories for conducting experiments and developing new chemical processes. It is particularly useful in the synthesis of novel compounds and the study of reaction mechanisms.
Used in Pharmaceutical Industry:
CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& is used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its high purity and reactivity make it suitable for the production of high-quality drugs.
Used in Agrochemical Industry:
In the agrochemical industry, CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& is used in the synthesis of various agrochemicals, such as pesticides and herbicides. Its high purity and reactivity contribute to the development of effective and safe agrochemical products.
It is important to handle CYCLOHEXANE-1 4-DICARBONITRILE 98% MIXT& with care and follow proper safety precautions due to its potential hazards and toxicity.

InChI:InChI=1/C8H10N2/c9-5-7-1-2-8(6-10)4-3-7/h7-8H,1-4H2

Upstream product

• 619-81-8 cyclohexane-1,4-dicarboxylic acid 
• 4848-16-2 4-cyano-cyclohexane carboxylic acid 
• 105-08-8 bis-1,4-(hydroxymethyl)cyclohexane 
• 20101-86-4 transcyclohexane-1,4-dicarboxylic acid amide 
• 2549-93-1 1,4-bis-(aminomethyl)cyclohexane 
• 224048-17-3 1-cyclohexyl-3-ethyl-6-fluoro-1H-indazole 
• 40949-94-8 potassium hexamethylsilazane 

Downstream Products

• 35027-32-8 N-[(1,4-Dicyano-cyclohexyl)-diphenyl-methyl]-benzamide 
• 35027-33-9 C₄₈H₄₀N₄O₂ 
• 10029-09-1 cis-cyclohexane-1,4-diyldimethanamine 
• 10029-07-9 trans-1,4-cyclohexane-bis(methylamine) 
• 2549-93-1 1,4-bis-(aminomethyl)cyclohexane 
• 6550-85-2 trans-1,4-cyclohexanedicarbonitrile 

Relevant academic research and scientific papers

METHOD FOR PRODUCING DICYANOCYCLOHEXANE AND BIS(AMINOMETHYL)CYCLOHEXANE

The problem addressed by this invention is to achieve a useful and novel method for producing dicyanocyclohexane and bis(aminomethyl)cyclohexane. This problem was solved by providing a method for producing dicyanocyclohexane having a cyanation step in which dicyanocyclohexane is obtained by a cyanation reaction of cyanocyclohexane-1-carboxylic acid and/or a salt thereof with an ammonia source, and a method for producing bis(aminomethyl)cyclohexane using the dicyanocyclohexane thus produced.

PRODUCTION METHOD FOR DICYANOCYCLOHEXANE

The present invention provides a production method for dicyanocyclohexane, including a step of obtaining dicyanocyclohexane by reacting cyclohexanedicarboxylic acid and/or a salt thereof, or a heated concentrate of an aqueous ammonia solution of cyclohexanedicarboxylic acid with ammonia in a solvent having a boiling point equal to or higher than a reaction temperature.

METHOD FOR PRODUCING 1,4-DICYANOCYCLOHEXANE, 1,4-BIS(AMINOMETHYL)CYCLOHEXANE AND 1,4-CYCLOHEXANEDICARBOXYLIC ACID

A method for producing 1,4-dicyanocyclohexane, having a step of obtaining 1,4-dicyanocyclohexane by subjecting a heated concentrate of an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to a cyanation reaction.

Method for catalyzing ammoxidation cracking of 1,4-cyclohexanedimethanol to prepare 1,4-cyclohexanedicarbonitrile

The invention relates to a method for catalyzing ammoxidation cracking of 1,4-cyclohexanedimethanol to prepare 1,4-cyclohexanedicarbonitrile.The method uses ammonia as nitrogen source and uses air and/or oxygen as oxygen source, 1,4-cyclohexanedimethanol is ammoxidized to 1,4-cyclohexanedicarbonitrile under catalyst action. The method provided by the invention has high ammonia oxidation efficiencyand high product yield, uses air as oxygen source and is economical and environmental protection. The product and catalyst are easy to separate, and the post-treatment is simple, so the method has agood application prospect.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

"Nanorust"-catalyzed benign oxidation of amines for selective synthesis of nitriles

Organic nitriles constitute key precursors and central intermediates in organic synthesis. In addition, nitriles represent a versatile motif found in numerous medicinally and biologically important compounds. Generally, these nitriles are synthesized by traditional cyanation procedures using toxic cyanides. Herein, we report the selective and environmentally benign oxidative conversion of primary amines for the synthesis of structurally diverse aromatic, aliphatic and heterocyclic nitriles using a reusable "nanorust" (nanoscale Fe2O3)-based catalysts applying molecular oxygen.

Substituted indazole derivatives and related compounds

The invention relates to compounds of the formula I and pharmaceutically acceptable salts thereof, wherein R2aand R2bare independently selected from the group consisting essentially of hydrogen and hereinafter recited substituents, provided that one, but not both of R2aand R2bmust be independently selected as hydrogen, wherein said substituents comprise: wherein the dashed lines in formulas (Ia) and (Ib) independently and optionally represent a single or double bond, provided that in formula (Ia) both dashed lines cannot both represent double bonds at the same time; and R, R1, R3, R4, R5, R6, R7, R18and m are as defined. The invention further relates to intermediates for the preparation of the compounds of formula I, and to pharmaceutical compositions containing, and methods of using, the compounds of formula I, or acceptable salts thereof, for the inhibition of phosphodiesterase (PDE) type IV or the production of tumor necrosis factor (TNF) in a mammal.