105350-26-3

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Basic information

Product Name: 2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE
Synonyms: SR 2640 HYDROCHLORIDE;2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE;SR2640HCl;2-[3-(2-Quinolylmethoxy)phenylamino]benzoic acid hydrochloride;2-[[3-[(Quinolin-2-yl)methoxy]phenyl]amino]benzoic acid;2-((3-(Quinolin-2-ylMethoxy)phenyl)aMino)benzoic acid hydrochloride
CAS NO:105350-26-3
Molecular Formula: C23H19ClN2O3
Molecular Weight: 406.86
EINECS: N/A
Product Categories: Prostanoid receptor and related
Mol File: 105350-26-3.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: 580.3ºC
Flash Point: 304.7 ºC
Appearance: yellow, powder with a tan cast/solid
Density: 1.322 g/cm3
Vapor Pressure: 2.63E-14mmHg at 25°C
Refractive Index: 1.711
Storage Temp.: 2-8°C
Solubility: DMSO: 50 mg/mL, soluble
PKA: 3.67±0.36(Predicted)
Stability: Hygroscopic
CAS DataBase Reference: 2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE(CAS DataBase Reference)
NIST Chemistry Reference: 2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE(105350-26-3)
EPA Substance Registry System: 2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE(105350-26-3)

Safety Data

Hazard Codes: Xi
Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 105350-26-3(Hazardous Substances Data)

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SR 2640 Hydrochloride
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Dayang Chem (Hangzhou) Co.,Ltd.
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Benzoic acid,2-[[3-(2-quinolinylmethoxy)phenyl]amino]-
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Hangzhou J&H Chemical Co., Ltd.
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SR 2640 hydrochloride;2-[[3-(2-QuinolinylMethoxy)phenyl]aMino]benzoicacidhydrochloride
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Wuxi Morality Chemical Co., Ltd
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SR 2640 hydrochloride,2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoicacidhydrochloride
Cas No: 105350-26-3
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NovaChemistry
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2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE
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Tocris Bioscience
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105350-26-3 Usage

Uses

SR 2640 Hydrochloride is a useful intermediate. It is a potent, selective LTD4 /LTE4 receptor antagonist.

Biological Activity

Potent and selective competitive leukotriene D 4 and E 4 receptor antagonist. Inhibits LTD 4 - but not histamine-induced guinea pig ileum and trachea contraction (pA 2 = 8.7). Also inhibits LTD 4 -attenuation of human PMN chemotaxis. Orally active in vivo .

Check Digit Verification of cas no

The CAS Registry Mumber 105350-26-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,5 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 105350-26:
(8*1)+(7*0)+(6*5)+(5*3)+(4*5)+(3*0)+(2*2)+(1*6)=83
83 % 10 = 3
So 105350-26-3 is a valid CAS Registry Number.

InChI:InChI=1/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)

105350-26-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	SR 2640 hydrochloride,2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoicacidhydrochloride

1.2 Other means of identification

Product number	-
Other names	SR2640HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105350-26-3 SDS

105350-26-3Upstream product

105350-26-3Downstream Products

105350-26-3Relevant articles and documents

Pyridyl and quinoline derivatives

-

, (2008/06/13)

The present invention relates to compounds of formula I STR1 in which formula I X stands for O, S, STR2 R1 and R2 which can be the same or different stand for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or

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