105355-37-1

Basic information

• Product Name: 3-chloro-4-((5-chloropyrimidin-2-yl)oxy)aniline
• CAS NO: 105355-37-1
• Molecular Weight: 256.091
• Mol File: 105355-37-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-chloro-4-((5-chloropyrimidin-2-yl)oxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-4-((5-chloropyrimidin-2-yl)oxy)aniline(105355-37-1)
• EPA Substance Registry System: 3-chloro-4-((5-chloropyrimidin-2-yl)oxy)aniline(105355-37-1)

Safety Data

• Hazardous Substances Data: 105355-37-1(Hazardous Substances Data)

Upstream product

• 22536-67-0 2,5-dichloropyrimidine 
• 3964-52-1 2-chloro 4-aminophenol 

Downstream Products

• 105355-36-0 N-(2-nitrobenzoyl)-N'-[3-chloro-4-(5-chloro-2-pyrimidinyloxy)phenyl]urea 

Relevant articles and documents

hTERT MODULATORS AND METHODS OF USE

The present invention provides hTERT modulators and methods for producing and using the same. In particular, the present invention provide a compound of the formula as described herein. Some aspects of the invention are based on the characterization of the effect of hTERT core promoter region mutants on the 5-12 G-quadruplex structure and its stability. It is believed that some of the compounds of the invention bind selectively to the G-quadruplex in the hTERT core promoter mutant, which results in reversal of the effect of mutant promoter activation.