105357-17-3Relevant articles and documents
Method of stimulating superoxide generation
-
, (2008/06/13)
The present invention is directed to a method of stimulating superoxide generation using phenolic thioethers which stimulate the generation of superoxide.
Acylaminoalkylpyridines ad use in treatment of inflammation and allergy reactions
-
, (2008/06/13)
The compounds of this invention are acylaminoalkylpyridines representd by the formula STR1 wherein: R1 and R2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a STR2 group wherein n, m and p are independently an integer of from 1 to 8 provided n+m+p is equal to or less than 10; X is thio, sulfinyl or sulfonyl; Alk1 is straight or branched chain lower alkylene of 1 to 6 carbon atoms, R3 is lower alkyl, Alk2 is straight or branched chain alkylene of 1 to 4 carbon atoms; R4 is selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl and lower alkoxy; and the pharmaceutically acceptable salts thereof. The compounds of the present invention are useful in the treatment of inflammation, allergy and hypersensitivity reactions and other disorders of the immune system.