105359-25-9

Basic information

• Product Name: (3SR,4SR,5SR)-2-cyclohexyl-5,6-epoxy-4-hydroxy-6-methyl-3-methylthiohept-1,5-diene
• Synonyms: (3SR,4SR,5SR)-2-cyclohexyl-5,6-epoxy-4-hydroxy-6-methyl-3-methylthiohept-1,5-diene
• CAS NO: 105359-25-9
• Molecular Weight: 270.436
• Mol File: 105359-25-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3SR,4SR,5SR)-2-cyclohexyl-5,6-epoxy-4-hydroxy-6-methyl-3-methylthiohept-1,5-diene(CAS DataBase Reference)
• NIST Chemistry Reference: (3SR,4SR,5SR)-2-cyclohexyl-5,6-epoxy-4-hydroxy-6-methyl-3-methylthiohept-1,5-diene(105359-25-9)
• EPA Substance Registry System: (3SR,4SR,5SR)-2-cyclohexyl-5,6-epoxy-4-hydroxy-6-methyl-3-methylthiohept-1,5-diene(105359-25-9)

Safety Data

• Hazardous Substances Data: 105359-25-9(Hazardous Substances Data)

Upstream product

• 5369-62-0 (+/-)-3,3-dimethyloxirane-2-carboxaldehyde 
• 162086-79-5 2-cyclohexyl-1-methylthioprop-2-ene 
• 162086-78-4 (3-bromoprop-1-en-2-yl)cyclohexane 
• 7697-55-4 2-cyclohexylprop-2-en-1-ol 

Downstream Products

• 105359-21-5 (2S,2'R,3'R)-3'-(1-Cyclohexyl-vinyl)-3,3-dimethyl-[2,2']bioxiranyl 

Relevant articles and documents

Total Synthesis of Natural (+)-Spatol. Confirmation of The Absolute Stereostructure

Total synthesis of optically pure spatol (+)-1 was achieved by employing asymmetric (2+2) photocycloaddition of the optically pure 12 with cyclopentenone ethylene ketal.The two major photocycloadducts 14, 15 were separately converted into the cis,anti,cis-tricyclo2,6>decane 9 and then to the sulfonium 11.Coupling of 11 through ylide with optically active epoxyaldehyde 24 provided optically pure 1 with definite absolute configuration.