1053659-39-4

Basic information

• Product Name: 3-Bromo-6-chloropicolinonitrile, 97%
• Synonyms: 3-Bromo-6-chloropicolinonitrile, 97%;3-Bromo-6-chloro-2-cyanopyridine, 3-Bromo-6-chloropicolinonitrile;3-Bromo-6-chloropyridine-2-carbonitrile97%;3-Bromo-6-chloro-2-pyridinecarbonitrile
• CAS NO: 1053659-39-4
• Molecular Formula: C₆H₂BrClN₂
• Molecular Weight: 217
• Mol File: 1053659-39-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 87-92°C
• Boiling Point: 111-113°C/0.15 mmHg
• Appearance: /
• Density: 1.85±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -8.16±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-6-chloropicolinonitrile, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-6-chloropicolinonitrile, 97%(1053659-39-4)
• EPA Substance Registry System: 3-Bromo-6-chloropicolinonitrile, 97%(1053659-39-4)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-37/38-41
• Safety Statements: 26-39-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1053659-39-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-chloropicolinonitrile, 97% is a specialized chemical compound with a high level of purity, as indicated by the 97% in its name. The compound is part of the larger family of picolinonitriles, which are a series of heterocyclic organic compounds containing a pyridine ring bearing a cyano group and a bromo group at the 3rd and 6th positions respectively. They are primarily used in research and development settings, where they contribute to a wide range of scientific and industrial applications. Due to the presence of bromine and chlorine atoms, the compound displays unique chemical properties. Its applications can include the synthesis of various pharmaceuticals, agrochemicals, and other complex organic molecules. Handling and use of such chemicals necessitates a firm understanding of safety procedures due to their reactivity and potential hazards.

Upstream product

• 53939-30-3 5-bromo-2-chloropyridine 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 889865-43-4 5-bromo-2-chloropyridine 1-oxide 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 1290059-08-3 5-benzoyl-3-bromo-6-chloro-4-methylthiopicolinonitrile 
• 929000-66-8 3-bromo-6-chloropyridine-2-carboxylic acid 
• 1276688-39-1 6-chloro-3-(2-(4-(N,N-dimethylamino)phenyl)ethynyl)picolinonitrile 
• 1276688-40-4 3,6-bis(2-(4-(N,N-dimethylamino)phenyl)ethynyl)picolinonitrile 
• 58300-70-2 bis(p-dimethylaminophenyl)butadiyne 

Relevant articles and documents

Homogenous suspension of immunopotentiating compounds and uses thereof

The present invention generally relates to homogeneous suspensions of small molecule immune potentiators (SMIPs) that are capable of stimulating or modulating an immune response in a subject in need thereof. The homogeneous suspensions may be used in combinations with various antigens or adjuvants for vaccine therapies.

COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N; X4 is N Or CR3; X5 is -CR4=CR5.