105380-81-2

Basic information

• Product Name: 5'-O-trityl-2,3'-anhydro-2'-deoxy-5-ethyluridine
• Synonyms: 5'-O-trityl-2,3'-anhydro-2'-deoxy-5-ethyluridine
• CAS NO: 105380-81-2
• Molecular Weight: 480.563
• Mol File: 105380-81-2.mol

Chemical Properties

• CAS DataBase Reference: 5'-O-trityl-2,3'-anhydro-2'-deoxy-5-ethyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-trityl-2,3'-anhydro-2'-deoxy-5-ethyluridine(105380-81-2)
• EPA Substance Registry System: 5'-O-trityl-2,3'-anhydro-2'-deoxy-5-ethyluridine(105380-81-2)

Safety Data

• Hazardous Substances Data: 105380-81-2(Hazardous Substances Data)

Upstream product

• 15176-29-1 edoxudine 
• 67912-88-3 5'-O-Trityl-5-ethyl-2'-deoxyuridine 
• 108895-47-2 1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentafuranosyl)-5-ethyluracil 

Downstream Products

• 67912-88-3 5'-O-Trityl-5-ethyl-2'-deoxyuridine 
• 105380-82-3 3'-azido-5-ethyl-5'-O-trityl-2',3'-dideoxyuridine 

Relevant articles and documents

NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY

The invention relates to special nucleosides, for example, a nucleoside of the formula I, wherein R1-R5 are as described herein, and also to drugs which contain these nucleosides. Furthermore, the invention relates to the use of such nucleosides in a method for suppressing or reducing the formation of resistance in the case of cytostatic treatment of a cancer patient.

Structure-Activity Relationships of Pyrimidine Nucleosides as Antiviral Agents for Human Immunodeficiency Virus Type 1 in Peripheral Blood Mononuclear Cells

The structure-activity relationships of several pyrimidine nucleosides related to 3'-azido-3'-deoxythymidine (AZT) were determined in human immunodeficiency virus type 1 (HIV-1) infected human peripheral blood mononuclear cells.These studies indicated tha