105392-26-5 Usage
Chemical Properties
White or off-white crystalline powder
Check Digit Verification of cas no
The CAS Registry Mumber 105392-26-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,9 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 105392-26:
(8*1)+(7*0)+(6*5)+(5*3)+(4*9)+(3*2)+(2*2)+(1*6)=105
105 % 10 = 5
So 105392-26-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H12Cl2FNO3/c1-21-14(20)9(6-18-7-2-3-7)13(19)8-4-12(17)11(16)5-10(8)15/h4-7,18H,2-3H2,1H3/b9-6-
105392-26-5Relevant articles and documents
Cycloaracylation of Enamines, I. - Synthesis of 4-Quinolone-3-carboxylic Acids
Grohe, Klaus,Heitzer, Helmut
, p. 29 - 37 (2007/10/02)
Starting with o-halobenzoyl chlorides 4 and open-chain secondary enamines 5, a new synthesis of 4-quinolone-3-carboxylic acids 12 is described.The reaction of 7-haloquinolone-3-carboxylic acids 12a-k with aliphatic amines 14 produces highly active antibacterial 7-aminoquinolone-3-carboxylic acids 15.The main product of the 1-cyclopropyl series, "ciprofloxacin" (15a), is being developed as a broad-spectrum chemotherapeutic agent.