105401-49-8

Basic information

• Product Name: 4-(2,5-dimethylphenoxy)butanoic acid
• Synonyms: 4-(2,5-dimethylphenoxy)butanoic acid
• CAS NO: 105401-49-8
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25364
• Mol File: 105401-49-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2,5-dimethylphenoxy)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,5-dimethylphenoxy)butanoic acid(105401-49-8)
• EPA Substance Registry System: 4-(2,5-dimethylphenoxy)butanoic acid(105401-49-8)

Safety Data

• Hazardous Substances Data: 105401-49-8(Hazardous Substances Data)

Usage

Class

Phenoxyalkanoic acids

Use

Herbicide in agriculture

Mode of action

Inhibiting growth of certain plants by interfering with auxin synthesis

Other potential properties

Anti-inflammatory and anti-cancer effects

Production

Chemical synthesis

Presence in herbicide products

Used in agriculture

Upstream product

• 95-87-4 2,5-Dimethylphenol 

Relevant articles and documents

Gemfibrozil derivatives as activators of soluble guanylyl cyclase – A structure-activity study

Previous studies demonstrated that anti-hyperlipidemic drug gemfibrozil acts as NO- and heme-independent activator of NO receptor soluble guanylyl cyclase. A series of new gemfibrozil derivatives were synthesized and evaluated for sGC activation. The structure-activity relationship study identified the positions in gemfibrozil's scaffold that are detrimental for sGC activation and those that are amendable for optimizing modifications. Compared with gemfibrozil, compounds 7c and 15b were more potent activators of cGMP-forming activity of purified sGC and exhibited enhanced relaxation of preconstricted mouse thoracic aorta rings. These studies established the overall framework needed for futher improvement of sGC activators based on gemfibrozil scaffold.