105448-19-9Relevant academic research and scientific papers
Synthesis and biological activity of 5-phenyl-1,3,4-benzotriazepines. 14. The reactions of 2-thioxo-5-phenyl-1,3,4-benzotriazepines
Morgenstern,Besch,Richter
, p. 760 - 761 (2007/10/02)
The interaction of 2-aminoethanol and 2-thioxo-5-phenyl-1,3,4-benzotriazepines in abs. dioxane under refluxing conditions was investigated. Depending on the substitution of the triazepine ring several products are formed. The S-N-exchange to form the corresponding 2-(2-hydroxyethyl)-amino derivatives only takes place if the nitrogen atoms of the heterocycle are unsubstituted.
