1054483-78-1

Basic information

• Product Name: 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
• Synonyms: 2-HYDROXYPYRIDINE-5-BORONIC ACID, PINACOL ESTER;2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE;6-HYDROXY-PYRIDINE-3-BORONIC ACID, PINACOL ESTER;6-HYDROXYPYRIDIN-3-YLBORONIC ACID, PINACOL ESTER;5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol;6-Hydroxypyridine-3-boronic acid, pinacol ester, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol;2-Hydroxypyridin-5-ylboronic acid pinacol ester;5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-2-hydroxypyridine
• CAS NO: 1054483-78-1
• Molecular Formula: C₁₁H₁₆BNO₃
• Molecular Weight: 221.06
• EINECS: 214-589-6
• Product Categories: Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents
• Mol File: 1054483-78-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 197-198
• Boiling Point: 401.1 °C at 760 mmHg
• Flash Point: 196.4 °C
• Appearance: /
• Density: 1.13 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 11.98±0.10(Predicted)
• CAS DataBase Reference: 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE(1054483-78-1)
• EPA Substance Registry System: 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE(1054483-78-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-38-36
• Safety Statements: 26-36/37/39
• WGK Germany: 2
• Hazardous Substances Data: 1054483-78-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1054483-78-1 differently. You can refer to the following data:
1. 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is used in the preparation of modified C3 Betulinic acid (B330250) derivatives as HIV maturation inhibitors.
2. 6-Hydroxypyridine-3-boronic acid pinacol ester can be used as a reactant:In the synthesis of novel glutamate transporter EAAT2 activators.To prepare crizotinib derivatives as SHIP2 inhibitors.

Downstream Products

• 1092367-99-1 N-(2-chloro-6-methylphenyl)-2-(6-(6-hydroxypyridin-3-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide 
• 1246361-40-9 tert-butyl (2R)-4-(3-(7-chloro-4-fluoro-1-(3-methoxypropyl)-3-methyl-1H-indol-2-yl)piperidin-1-yl)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-oxobutan-2-ylcarbamate 
• 1246361-58-9 tert-butyl (2R)-4-(3-(4-fluoro-1-(3-methoxypropyl)-1H-indol-2-yl)piperidin-1-yl)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-oxobutan-2-ylcarbamate 
• 1246362-16-2 tert-butyl (2R)-4-(3-(4-fluoro-1-(3-methoxypropyl)-3-methyl-1H-indol-2-yl)piperidin-1-yl)-1-(2-fluoro-4-(6-hydroxypyridin-3-yl)phenyl)-4-oxobutan-2-ylcarbamate 
• 1246362-24-2 tert-butyl (2R)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-(3-(1-(3-methoxypropyl)-7-methyl-3-(trifluoromethyl)-1H-indol-2-yl)piperidin-1-yl)-4-oxobutan-2-ylcarbamate 
• 1246362-31-1 tert-butyl (2R)-4-(3-(4-(benzyloxy)-1-(3-methoxypropyl)-1H-indol-2-yl)piperidin-1-yl)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-oxobutan-2-ylcarbamate 
• 1246362-35-5 tert-butyl (R)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-((R)-3-(1-(3-methoxypropyl)-5-methyl-3,4-bis(trifluoromethyl)-1H-pyrrol-2-yl)piperidin-1-yl)-4-oxobutan-2-ylcarbamate 
• 1246361-25-0 tert-butyl (2R)-4-(3-(6-fluoro-1-(3-methoxypropyl)-1H-indol-2-yl)piperidin-1-yl)-1-(4-(6-hydroxypyridin-3-yl)phenyl)-4-oxobutan-2-ylcarbamate 
• 381233-78-9 5-(2-Pyridyl)-1,2-dihydropyridin-2-one 
• 1338225-44-7 C₁₈H₁₆N₂S 
• 1616917-84-0 (E)-5-cinnamylpyridine-2-ol 
• 1616917-83-9 (E)-2-(cinnamyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 1333222-12-0 2-difluoromethoxy-5-(4,4,5,5-tetramethyl-[1 ,3,2]dioxaborolan-2-yl)-pyridine