10545-00-3Relevant academic research and scientific papers
Pentadienyltitaniums as versatile intermediates: Regio- and stereoselectivities
Zellner,Schlosser
, p. 1016 - 1018 (2007/10/03)
The adduct obtained upon consecutive treatment of 1,4-dienes with butyllithium in the presence of potassium tert-butoxide, chlorotri(isopropyloxy)titanium and a carbonyl compound contains the α-hydroxyalkyl group invariably and exclusively linked to the 3-position of the former diene. When chlorotri(isopropyloxy)titanium is replaced by the Duthaler-Hafner reagent [(4R,5R)-chloro(cyclopentadienyl)(2,2-dimethyl-α,α,α ′,α′-tetraphenyl-1,3-dioxolane- 4,5-dimethanolato-O,Oα)titanium] the reaction does not only occur regioselectively but also with appreciably high enantioselectivity.
A highly efficient and practical preparation of 2,4-pentadienyltitaniums and their γ-selective addition reaction with aldehydes and ketones
Okamoto, Sentaro,Sato, Fumie
, p. 151 - 156 (2007/10/03)
A variety of penta-2,4-dienyltitanium complexes including those having a functional group were readily prepared from a divalent titanium reagent, Ti(O-i-Pr)4/2i-PrMgCl, and penta-1,4-dien-3-ol or penta-2,4-dien-1-ol derivatives, and the organotitaniums thus prepared reacted with aldehydes and ketones smoothly to afford the corresponding penta-1,4-dien-3-yl carbinols highly predominantly in excellent yield.
Indium-mediated γ-pentadienylation of aldehydes and ketones: Cross-conjugated trienes for diene-transmissive cycloadditions
Woo, Simon,Squires, Neil,Fallis, Alex G.
, p. 573 - 575 (2008/02/11)
(Matrix presented) Treatment of 5-bromo-1,3-pentadiene with indium metal in the presence of carbonyl compounds results in γ-pentadienylation to generate the 1,4-diene. Elimination of the resulting alcohol affords cross-conjugated triene systems which rapi
