1054547-10-2Relevant academic research and scientific papers
Mechanism and regioselectivity of the cycloaddition of thiones derived from meldrum's acid, malonates, or other dicarbonyls
Perreault, Stephane,Poirier, Maude,Leveille, Pascal,Rene, Olivier,Joly, Pascal,Dory, Yves,Spino, Claude
, p. 7457 - 7466 (2008)
(Chemical Equation Presented) Several α,α-dioxothiones were generated in situ and reacted with 1,3-dienes of varying electronic and steric properties. It was found that thiones 10a and 11a reacted well with electron-rich or electron-poor dienes and are complementary in their regioselectivities when steric effects are at play. The calculated preferred mechanistic pathway implies a thiiranium zwitterion intermediate.
