1054648-05-3Relevant articles and documents
Engineering strategy to improve peptide analogs: From structure-based computational design to tumor homing
Zanuy, David,Sayago, Francisco J.,Revilla-Lopez, Guillem,Ballano, Gema,Agemy, Lilach,Kotamraju, Venkata Ramana,Jimenez, Ana I.,Cativiela, Carlos,Nussinov, Ruth,Sawvel, April M.,Stucky, Galen,Ruoslahti, Erkki,Aleman, Carlos
, p. 31 - 43 (2013)
We present a chemical strategy to engineer analogs of the tumor-homing peptide CREKA (Cys-Arg-Glu-Lys-Ala), which binds to fibrin and fibrin-associated clotted plasma proteins in tumor vessels (Simberg et al. in Proc Natl Acad Sci USA 104:932-936, 2007) w