1054653-06-3Relevant academic research and scientific papers
HIV-1 protease inhibitors based on acyclic carbohydrates
Zuccarello, Guido,Bouzide, Abderrahim,Kvarnstroem, Ingemar,Niklasson, Gunilla,Svensson, Stefan C. T.,Brisander, Magnus,Danielsson, Helena,Nillroth, Ulrika,Karlen, Anders,Hallberg, Anders,Classon, Bjoern,Samuelsson, Bertil
, p. 4898 - 4906 (2007/10/03)
A series of acyclic C2-symmetric HIV protease inhibitors readily accessible from D-mannitol have been developed. Several of the compounds synthesized showed significant in vitro activity against HIV-1 protease.
