10548-71-7Relevant academic research and scientific papers
Enantioselective addition of diethylzinc to aldehydes using γ-aminoalcohols derived from α-D-xylose as new chiral catalysts
Cho, Byung Tae,Kim, Namdu
, p. 4115 - 4118 (1994)
The enantioselective addition of diethylzinc to aldehydes using 1,2-isopropylidene-5-deoxy-5-dialkylamino-α-D-xylofuranoses derived from α-D-xylose as new catalysts provided the corresponding alcohols with 75-96% ee.
Enantioselective arylations catalyzed by carbohydrate-based chiral amino alcohols
Wouters, Ana Dioneia,Trossini, Gustavo H. G.,Stefani, Helio A.,Luedtke, Diogo S.
scheme or table, p. 2351 - 2356 (2010/07/04)
The application of carbohydrate-derived amino alcohols in the asymmetric arylation of aldehydes by using arylboronic acids as the source of transferable aryl groups is described. The best ligand is derived from the readily available sugar D-xylose and it mediates the addition of a range of arylboronic acids to various aromatic aldehydes in excellent yields and high enantiomeric excesses.
Catalytic enantioselective reactions. Part 9. 1,2-O-isopropylidene-5-deoxy-5-N,N-dialkyl (or -N-monoalkyl)amino-α-D-xylofuranose derivatives as highly effective chiral catalysts for enantioselective addition of diethylzinc to aliphatic and aromatic aldehydes
Cho, Byung Tae,Kim, Namdu
, p. 2901 - 2907 (2007/10/03)
A series of new 1,2-O-isopropylidene-5-deoxy-5-N,N-dialkyl (or -N-monoalkyl)amino-α-D-xylofuranose derivatives have been prepared from α-D-xylose and their enantioselectivities as chiral catalysts for the addition of diethylzinc to aldehydes have been examined. Of the chiral catalysts examined, 5-deoxy-1,2-O-isopropylidene-5-morpholino-α-D-xylofuranose provides high enantioselectivity for aromatic and relatively hindered aliphatic aldehydes, and 5-deoxy-5-hexahydroazepinyl-1,2-O-isopropylidene-α-D-xylofuranose is highly effective for unhindered aliphatic aldehydes.
