105481-61-6Relevant academic research and scientific papers
METABOLITES PRODUCED BY THE SCLERODERRIS CANKER FUNGUS, GREMMENIELLA ABIETINA. PART 4. BIOSYNTHETIC STUDIES
Ayer, William A.,Pedras, M. Soledade,Ward, Dale E.
, p. 760 - 764 (2007/10/02)
The biosynthetic origin of the carbon atoms of the most highly oxidized, polyketide derived, ring (carbon 1-3) of the Gremmeniella abietina metabolites sclerodione (3), scleroderolide (4), sclerodin (5), and Scleroderris green (6) has been studied.It is shown that both C-1 and C-3 of 3 and 4 are derived from C-1 of acetate, and that C-2 of scleroderolide (4) is derived fom C-2 acetate while C-3 is derived from C-1 of acetate.As expected, C-1 and C-3 of Scleroderris green (6) originate from the carboxyl carbon of acetate, while C-2 originates from the methyl carbon of acetate.Complete 13C and 1H nuclear magnetic resonance spectra of these metabolites are reported.It has also been shown that ent-atrovenetin (ent-7a) is a metabolite of G. abietina.
