10549-12-9Relevant academic research and scientific papers
Simple and efficient preparation of (R)- and (S)-enantiomers of α-carbon deuterium-labelled α-amino acids
Mitulovi, Goran,Laemmerhofer, Michael,Maier,Lindner, Wolfgang
, p. 449 - 461 (2007/10/03)
A procedure for the synthesis of (R)- and (S)-enantiomers of α-carbon deuterium-labelled α-amino acids, exemplified for (R)- and (S)-[2-2H1]-Leu is described. Starting from the respective (S)- or (R)-enantiomer or from the racemic mixture of an α-amino acid the selective proton exchange at the α-carbon is carried out by racemization via a Schiff base in monodeuterated acetic acid as solvent which serves as deuterium source. After N-protection the racemic mixture is liquid chromatographically separated into the individual (R)- and (S)-enantiomers on preparative scale employing a chiral anion exchanger based on carbamoylated quinine as chiral selector. After deprotection the enantiomerically pure products can be obtained in good yields.
Bacteriochlorophyll f. - Partial Synthesis and the Behaviour of Some Derivatives
Risch, Nikolaus,Koester, Bettina,Schormann, Anette,Siemens, Thomas,Brockmann, Hans
, p. 343 - 348 (2007/10/02)
Starting with chlorophyll a/b mixture 5/6 from green plants, we describe the partial synthesis of the bacteriophaeophorbide f methyl ester 7.This is a derivative of bacteriochlorophyll f (4).We postulate the existence of 4 as a natural product, though it
