105500-34-3 Usage
Uses
Used in Pharmaceutical Development:
(R)-2-acetamido-3-acetoxypropanoic acid is used as a key component in the development of pharmaceuticals, particularly for targeting bacterial infections. Its presence in bacterial cell walls makes it a promising candidate for the creation of drugs that can specifically disrupt bacterial cell structures, potentially leading to the eradication of harmful bacteria.
Used in Carbohydrate Biology Research:
In the field of carbohydrate biology, (R)-2-acetamido-3-acetoxypropanoic acid is used as a research tool to study the structure, function, and interactions of glycoproteins and glycolipids. Understanding these complex molecules is essential for gaining insights into various biological processes and developing targeted therapies for a range of diseases.
Used in the Synthesis of Glycoproteins and Glycolipids:
(R)-2-acetamido-3-acetoxypropanoic acid is used as a building block for the synthesis of glycoproteins and glycolipids, which are essential for the structure and function of cell membranes. These biomolecules play a critical role in cell signaling, immune response, and cell adhesion, making them important targets for therapeutic intervention in various diseases.
Used in the Food Industry:
In the food industry, (R)-2-acetamido-3-acetoxypropanoic acid can be used as a component in the development of novel additives or functional ingredients that can enhance the nutritional value, texture, or shelf life of food products. Its role in the structure and function of cell membranes may also provide insights into the development of ingredients that promote gut health or other health benefits.
Used in the Cosmetics Industry:
(R)-2-acetamido-3-acetoxypropanoic acid may also find applications in the cosmetics industry, where it could be used as an ingredient in skincare products to promote skin health and repair. Its role in the formation of glycoproteins and glycolipids, which are essential for maintaining the integrity and function of cell membranes, makes it a potentially valuable component in the development of cosmetics that target skin rejuvenation and repair.
Check Digit Verification of cas no
The CAS Registry Mumber 105500-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,5,0 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 105500-34:
(8*1)+(7*0)+(6*5)+(5*5)+(4*0)+(3*0)+(2*3)+(1*4)=73
73 % 10 = 3
So 105500-34-3 is a valid CAS Registry Number.
105500-34-3Relevant academic research and scientific papers
A synthesis scheme for preparing method
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Paragraph 0020; 0046; 0047, (2017/07/19)
The invention provides a preparation method of lacosamide, which comprises following steps: (A) performing a reaction between D-serine and acetic anhydride to generate an intermediate product N,O-diacetyl-D-serine; (B) performing methylation to the N,O-diacetyl-D-serine to obtain N-acetyl-D-serine methyl ether; (C) carrying out a reaction to the N-acetyl-D-serine methyl ether with benzylamine to obtain (R)-2-acetamido-N-benzyl-3-methoxyl propionamide. The preparation method is short in reaction route, can avoid racemization, and is high in yield and purity of a reaction product.
Design and evaluation of affinity labels of functionalized amino acid anticonvulsants
LeTiran, Arnaud,Stables, James P.,Kohn, Harold
, p. 4762 - 4773 (2007/10/03)
Studies have shown that functionalized amino acids (FAA) exhibit outstanding activity in the maximal electroshock-induced seizure (MES) test in rodents. Affinity labels patterned in part after the potent antiepileptic (R)-N-benzyl-2-acetamido-3-methoxypropionamide ((R)-2) have been prepared as mechanistic probes to learn the pharmacological basis for FAA function. The chemical reactivity of the affinity labels with nucleophiles was assessed, and the labels were evaluated in in vitro radioligand assays and in the MES tests in rodents. The affinity labels did not bind to receptors known to effect seizure spread. Three affinity labels, (R,S)-N-benzyl-2-acetamido-6-isothiocyanatohexanamide ((R,S)-5), (R)-N-(4-isothiocyanatobenzyl)-2-acetamido-3-methoxypropionamide ((R)-6), and (R)-N-(3-isothiocyanatobenzyl)-2-acetamido-3-methoxy-propionamide ((R)-7), possessed excellent in vivo anticonvulsant activity and exhibited maximal activity at later time periods than typically observed for FAA. The anticonvulsant activity of 6 and 7 resided primarily in the (R)-enantiomer and the activity of (R)-6 and (R)-7 in rats (po) exceeded that of phenytoin. The chemical properties, pharmacological profile, and marked stereospecificity associated with 6 and 7 anticonvulsant activity make these compounds useful pharmacological tools for the study of the mode of action of FAA.
