1055041-35-4

Upstream product

• 50571-26-1 5'-O-dimethoxytritylthymidine 3'-H-phosphonate 
• 144874-49-7 3',5'-di-O-acetyl-N³-methylthymidine 
• 144874-50-0 3'-O-acetyl-5'-O-dimethoxytrityl-N³-methyl-4-thiothymidine 
• 144874-46-4 3',5'-di-O-acetyl-N³-methyl-4-thiothymidine 
• 144874-48-6 3'-O-acetyl-N³-methyl-4-thiothymidine 
• 144874-47-5 N-3-methyl-4-thiothymidine 
• 6979-97-1 3',5'-diacetylthymidine 

Relevant academic research and scientific papers

Synthesis of Deoxydinucleoside Phosphates Containing 4-Thio Substituted Pyrimidine Nucleobases

The preparations, by the hydrogenphosphonate approach in solution, of the five pyrimidine deoxydinucleoside monophosphates 14a, 14b, 16a, 16b and 17 containing a 4-thiosubstituted pyrimidine nucleobase at either their 3'- or 5'-end are described.These syntheses were conveniently accomplished using 4-thionucleoside derivatives having their sulfur function protected by S-pivaloyloxymethylation.The behaviour of unprotected 4-thionucleoside derivatives was also investigated and they were shown to give comparable overall yields.