1055041-74-1Relevant academic research and scientific papers
Thio effects on the departure of the 3′-linked ribonucleoside from diribonucleoside 3′,3′-phosphorodithioate diesters and triribonucleoside 3′,3′,5′-phosphoromonothioate triesters: Implications for ribozyme catalysis
Loennberg, Tuomas,Ora, Mikko,Virtanen, Sami,Loennberg, Harri
, p. 4614 - 4627 (2007)
To provide a solid chemical basis for the mechanistic interpretations of the thio effects observed for large ribozymes, the cleavage of triribonucleoside 3′,3′,5′-phosphoromonothioate triesters and diribonucleoside 3′,3′-phosphorodithioate diesters has be
Hydrolytic stability of 2′,3′-O-methyleneadenos-5′-yl 2′,5′-di-O-methylurid-3′-yl 5′-O-methylurid- 3′(2′)-yl phosphate: Implications to feasibility of existence of phosphate-branched RNA under physiological conditions
Loennberg, Tuomas,Kiiski, Johanna,Mikkola, Satu
, p. 1089 - 1096 (2007/10/03)
Hydrolytic reactions of 2′,3′-O-methyleneadenos-5′-yl 2′,5′-di-O-methylurid-3′-yl 5′-O-methylurid- 3′(2′)-yl phosphate (1a,b) have been followed by RP-HPLC over a wide pH range to evaluate the feasibility of occurrence of phosphate-branched RNA under phys
