105518-09-0Relevant articles and documents
Evaluation of some preparations of trialkoxyphthalic acid derivatives
Parker, Kathlyn A.,Spero, Denice M.,Koziski, Kathleen A.
, p. 183 - 188 (2007/10/02)
Several approaches to trialkoxyphthalic acid derivatives, potential intermediates in a fredericamycin synthesis, were tested. Sequences based on a Diels-Alder/retro Diels-Alder reaction, a cyanide addition to a quinone, an Elbe oxidation, and an amide-directed ortho-lithiation are discussed in terms of length, yields, convenience, and the versatility of the product of each.