105518-12-5

Basic information

• Product Name: BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-
• Synonyms: BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-;N,N-diethyl-2,4,5-trimethoxybenzamide
• CAS NO: 105518-12-5
• Molecular Formula: C₁₄H₂₁NO₄
• Molecular Weight: 267.32
• Mol File: 105518-12-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 424.1°C at 760 mmHg
• Flash Point: 210.3°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 2.13E-07mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-(105518-12-5)
• EPA Substance Registry System: BENZAMIDE, N,N-DIETHYL-2,4,5-TRIMETHOXY-(105518-12-5)

Safety Data

• Hazardous Substances Data: 105518-12-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H21NO4/c1-6-15(7-2)14(16)10-8-12(18-4)13(19-5)9-11(10)17-3/h8-9H,6-7H2,1-5H3

Upstream product

• 42833-66-9 2,4,5-trimethoxybenzoyl chloride 
• 109-89-7 diethylamine 
• 490-64-2 asaronic acid 
• 20029-76-9 methyl 2,4,5-trimethoxybenzoate 

Downstream Products

• 1206481-37-9 2-ethenyl-3,4,6-trimethoxybenzoic acid 
• 105518-14-7 N,N-diethyl-6-(hydroxymethyl)-2,4,5-trimethoxybenzamide 
• 112043-27-3 3-Benzenesulfonyl-4,5,7-trimethoxy-3H-isobenzofuran-1-one 
• 112043-26-2 4,5,7-Trimethoxy-3-phenylsulfanyl-3H-isobenzofuran-1-one 
• 33390-21-5 bikaverin 
• 105518-13-6 N,N-diethyl-2-formyl-3,4,6-trimethoxybenzamide 
• 106114-62-9 N,N-diethyl-2-hydroxy-3,4,6-trimethoxybenzamide 
• 136009-07-9 <1,4,5,6,8-pentamethoxy-3-(phenylethynyl)-2-naphthyl>-<1-(phenylseleno)cyclopentyl>methanone 
• 136009-11-5 3-hydroxy-3-(α-hydroxybenzyl)-4,5,6,8,9-pentamethoxyspiro<2H-benzindene-2,1'-cyclopentan>-1(3H)-one 
• 136009-06-8 2--1,4,5,6,8-pentamethoxy-3-(phenylethynyl)naphthalene 
• 136009-10-4 C₂₉H₃₀O₆ 
• 139219-28-6 3-benzylidene-4,5,6,8,9-pentamethoxyspiro-<2H-benzindene-2,1'-cyclopentan>-1(3H)-one 
• 136009-05-7 cyclopentyl-<1,4,5,6,8-pentamethoxy-3-(phenylethynyl)-2-naphthyl>methanone 
• 136009-04-6 α-cyclopentyl-α-<1,4,5,6,8-pentamethoxy-3-(phenylethynyl)-2-naphthyl>methanol 

Relevant articles and documents

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Total synthesis of (+,-)fredericamycin A

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Diels-Alder Approaches to Model Compounds Related to Fredericamycin A

A series of model compounds related to the antitumor and antibiotic compound fredericamycin A has been prepared.Spiro-2,5-dione (2) has been prepared and established as a novel spiro dienophile in the Diels-Alder reaction with 1,3-butadiene, Danishefsky's diene, a triacetoxy-substituted o-quinodimethane, and two isobenzofuran intermediates.Thus, the cycloaddition of 3-cyano-4,5,7-trimethoxy-1(3H)-isobenzofuranone (35) and 2 afforded 4,9-dihydroxy-5,6,8-trimethoxyspiroindene-2,1'-indan>-1,3-dione (38) in 62percent yield.This methodology provides a viable synthetic route to the quinone portion of fredericamycin A that contains the seven requisite oxygens.