105518-35-2Relevant articles and documents
Formation of Quaternary Centers via the Michael Reaction. Electronic Compensation for Steric Congestion
Holton, Robert A.,Williams, Andrew D.,Kennedy, Robert M.
, p. 5480 - 5482 (2007/10/02)
Compensation for steric bulk at the β-terminus of a Michael acceptor may be provided by the attachment of two elctron-withdrawing substituents at the α-terminus.The Michael reaction of ketone and ester enolates is useful for the preparation of contiguous