1055190-79-8

Basic information

• Product Name: 1-(3-(1-tert-butyl-5-phenyl-1H-pyrazol-3-yl)propyl)-4-(3,4-dimethylphenyl)piperazine
• CAS NO: 1055190-79-8
• Molecular Weight: 430.637
• Mol File: 1055190-79-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-(1-tert-butyl-5-phenyl-1H-pyrazol-3-yl)propyl)-4-(3,4-dimethylphenyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-(1-tert-butyl-5-phenyl-1H-pyrazol-3-yl)propyl)-4-(3,4-dimethylphenyl)piperazine(1055190-79-8)
• EPA Substance Registry System: 1-(3-(1-tert-butyl-5-phenyl-1H-pyrazol-3-yl)propyl)-4-(3,4-dimethylphenyl)piperazine(1055190-79-8)

Safety Data

• Hazardous Substances Data: 1055190-79-8(Hazardous Substances Data)

Upstream product

• 1055192-71-6 3-(1-tert-butyl-5-phenyl-1H-pyrazol-3-yl)propanal 
• 1014-05-7 1-(3,4-dimethylphenyl)piperazine 

Relevant articles and documents

PIPERAZINYL-PROPYL-PYRAZOLE DERIVATIVES AS DOPAMINE D4 RECEPTOR ANTAGONISTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

The present invention relates to a novel piperazinyl-propyl-pyrazole derivative, a method of its preparation and a pharmaceutically acceptable composition comprising the same. The novel piperazinyl-propyl-pyrazole derivative of the present invention has superior selective affinity for dopamine D4 receptor, can effectively inhibit psychotic behavior (cage climbing) induced by apomorphine, and has relatively low adverse effects in mouse rotarod test. Therefore, it can be developed as a therapeutic agent for the treatment and prevention of central nervous system (CNS) disorders, in particular, schizophrenia, attention deficit hyperactivity disorder, depression, stress diseases, panic disorder, phobia, obsessive-compulsive disorder, posttraumatic stress disorder, cognitive disorder, Alzheimer's disease, Parkinson's disease, anxiety, paraphrenia, mania, seizure disorder, personality disorder, migraine, drug addiction, alcohol addiction, obesity, eating disorder, and sleeping disorder.