105532-96-5

Basic information

• Product Name: 5-butyl-3,4-diphenyl-1H-pyrazole
• Synonyms: 5-butyl-3,4-diphenyl-1H-pyrazole
• CAS NO: 105532-96-5
• Molecular Weight: 276.381
• Mol File: 105532-96-5.mol

Chemical Properties

• CAS DataBase Reference: 5-butyl-3,4-diphenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-butyl-3,4-diphenyl-1H-pyrazole(105532-96-5)
• EPA Substance Registry System: 5-butyl-3,4-diphenyl-1H-pyrazole(105532-96-5)

Safety Data

• Hazardous Substances Data: 105532-96-5(Hazardous Substances Data)

Upstream product

• 18215-68-4 1,1-diphenylhept-2-yn-1-ol 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Relevant articles and documents

One-pot synthesis of pyrazoles through a four-step cascade sequence

A one-pot synthesis of 3,4,5- and 1,3,5-pyrazoles from tertiary propargylic alcohols and para-tolylsulfonohydrazide has been accomplished. The pyrazoles are formed through a four-step cascade sequence, including FeCl 3-catalyzed propargylic substitution, aza-Meyer-Schuster rearrangement, base-mediated 6πelectrocyclization, and thermal [1,5] sigmatropic shift. In this reaction, the 3,4,5- and 1,3,5-pyrazoles are produced selectively according to different substituents in the starting alcohols. A one-pot recipe: The synthesis of 3,4,5- and 1,3,5-pyrazoles from tertiary propargylic alcohols and para-tolylsulfonohydrazide has been accomplished. The pyrazoles are formed through a four-step cascade sequence (see figure), and are produced selectively according to different substituents in the starting alcohols.