1055325-40-0

Basic information

• Product Name: n-butyl (S)-2-hydroxy-4-iodobutanoate
• Synonyms: n-butyl (S)-2-hydroxy-4-iodobutanoate
• CAS NO: 1055325-40-0
• Molecular Weight: 286.11
• Mol File: 1055325-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: n-butyl (S)-2-hydroxy-4-iodobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: n-butyl (S)-2-hydroxy-4-iodobutanoate(1055325-40-0)
• EPA Substance Registry System: n-butyl (S)-2-hydroxy-4-iodobutanoate(1055325-40-0)

Safety Data

• Hazardous Substances Data: 1055325-40-0(Hazardous Substances Data)

Upstream product

• 52079-23-9 (3S)-3-hydroxydihydrofuran-2(3H)-one 
• 71-36-3 butan-1-ol 

Downstream Products

• 132513-51-0 n-butyl (S)-2-hydroxybutanoate 

Relevant articles and documents

A practical synthesis of the PPARα agonist, (R)-K-13675, starting from (S)-2-hydroxybutyrolactone

A practical synthesis of optically pure PPARα agonist, (R)-K-13675, is described. This process is based on the use of (S)-2-hydroxybutyrolactone, which can be transformed into the requisite n-butyl (S)-2-hydroxybutanoate in an efficient manner. A key reaction is the etherification between the phenol and n-butyl (S)-2-trifluoromethanesulfonyloxybutanoate to give the phenyl ether in excellent yield without loss of optical purity.