1055361-86-8

Basic information

• Product Name: 4-(4-formyl-2-methoxyphenoxy)-3-chlorobenzonitrile
• Synonyms: 4-(4-formyl-2-methoxyphenoxy)-3-chlorobenzonitrile
• CAS NO: 1055361-86-8
• Molecular Weight: 287.702
• Mol File: 1055361-86-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(4-formyl-2-methoxyphenoxy)-3-chlorobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-formyl-2-methoxyphenoxy)-3-chlorobenzonitrile(1055361-86-8)
• EPA Substance Registry System: 4-(4-formyl-2-methoxyphenoxy)-3-chlorobenzonitrile(1055361-86-8)

Safety Data

• Hazardous Substances Data: 1055361-86-8(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 117482-84-5 3-chloro-4-fluorobenzonitrile 

Downstream Products

• 1055361-55-1 4-[4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-chlorobenzonitrile 
• 1264752-10-4 3-chloro-4-(4-{(Z)-[4-{[2-(diethylamino)ethyl]amino}-2-oxo-1,3-thiazol-5(2H)-ylidene]methyl}-2-methoxyphenoxy)benzonitrile 

Relevant articles and documents

PROPHYLACTIC OR THERAPEUTIC AGENT FOR CANCER

A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has a superior activity as an estrogen-related receptor-α modulator, and is useful as a prophylactic or therapeutic agent for cancer.

SUBSTITUTED PHENOXY THIAZOLIDINEDIONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS

The present invention relates to compounds of Formula (I): methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.