105577-03-5Relevant academic research and scientific papers
The use of malononitrile in the synthesis of novel α-amino nitriles
Metwally,Mogieb
, p. 1901 - 1905 (2001)
Continuing earlier studies designed to obtain compounds of pharmaceutical interest, we used acetyl acetone (1, R = CH3) and ethyl acetoacetate (1, R=OEt) for the preparation of some novel α-amino nitriles (3, 6 and 7). The structures of the new
Efficient and divergent synthesis of polyfunctionalized 2-pyridones from β-keto amides
Gao, Baochang,Sun, Yufeng,Wang, Jun,Yuan, Zhigang,Zu, Liwu,Zhang, Xu,Liu, Wenbin
, p. 33625 - 33630 (2018/10/20)
Efficient and divergent one-pot synthesis of polyfunctionalized 2-pyridones from β-keto amides based on reaction condition selection was developed. The methodology offers several significant advantages including mild conditions, ease of handling, high yie
SYNTHESIS OF PYRIDAZINE, PYRIDAZIN-3-ONE, 2-AMINOPYRROLE AND 2,5-DIAMINOPYRIDINE DERIVATIVES FROM DICYANOMETHYLENE COMPOUNDS
Abdelhamid, Abdou Osman,Abed, Nosrat Mostafa
, p. 101 - 107 (2007/10/02)
Aromatic diazonium chlorides react with dicyanomethylene compounds 1-3 and 18 to give the hydrazone derivatives which are readily cyclized into pyridazine 8-10 and pyridazine-3-one 19 respectively. 2-Aminopyrrole 11-13 and dihydropyridazin-3-one 20 are ob
