10560-45-9 Usage
Uses
Used in Cell Biology Research:
MTT is used as a viability assay indicator for assessing the metabolic activity of cells in cell biology research. It helps in determining the number of living cells in a culture, providing insights into cell growth and proliferation.
Used in Drug Development:
In the pharmaceutical industry, MTT is employed as a screening tool for evaluating the cytotoxic effects of new drug candidates. By measuring the reduction of MTT to formazan, researchers can assess the impact of drugs on cell viability, aiding in the development of safer and more effective medications.
Used in Toxicology Studies:
MTT is used as a bioassay reagent in toxicology studies to measure the toxicity of substances on cells. It helps in identifying potential hazards and understanding the mechanisms of toxicity, contributing to the safety assessment of chemicals and environmental pollutants.
It is crucial to handle MTT with care, as it poses potential hazards if inhaled, ingested, or if it comes into contact with the skin or eyes. Proper safety measures should be taken to minimize risks during its use in laboratory settings.
Check Digit Verification of cas no
The CAS Registry Mumber 10560-45-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,6 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10560-45:
(7*1)+(6*0)+(5*5)+(4*6)+(3*0)+(2*4)+(1*5)=69
69 % 10 = 9
So 10560-45-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H17N4O.ClH/c1-25-19-14-12-16(13-15-19)20-21-23(17-8-4-2-5-9-17)24(22-20)18-10-6-3-7-11-18;/h2-15H,1H3;1H/q+1;/p-1
10560-45-9Relevant academic research and scientific papers
1-Chlorobenzotriazole-Mediated Ring Closure of 1,3,5-Triarylformazans: Improved Syntheses of 2,3,5-Triaryl-2H-tetrazolium Salts
Katritzky, Alan R.,Belyakov, Sergey A.,Lam, Jamshed N.,Durst, H. Dupont,Karpenko, Dmitrii V.
, p. 73 - 80 (2007/10/02)
Oxidative ring closure of mono- and bis-triarylformazans mediated by easily available 1-chlorobenzotriazole leads to the corresponding 2,3,5-triaryl-2H-tetrazolium chlorides in yields of 70-97percent.
