105602-53-7

Upstream product

• 105602-54-8 (4S,5R)-5-Benzo[1,3]dioxol-5-yl-4-[(4-benzyloxy-3-methoxy-phenyl)-methoxy-methoxymethyl]-dihydro-furan-2-one 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 62848-90-2 trans-4-carboxy-5-(3,4-methylenedioxyphenyl)dihydrofuran-2(3H)-one 
• 16108-37-5 trans-4-hydroxymethyl-5-(3,4-methylenedioxyphenyl)-dihydrofuran-2(3H)-one 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 

Downstream Products

• 69742-32-1 (+/-)-styraxin 
• 105602-52-6 (R)-Benzo[1,3]dioxol-5-yl-[(3S,4S,5S)-5-(4-benzyloxy-3-methoxy-phenyl)-4-hydroxymethyl-tetrahydro-furan-3-yl]-methanol 
• 69742-32-1 (+/-)-epistyraxin 
• 105602-51-5 (+/-)-benzylpluviatilol 
• 28115-67-5 (+/-)-pluviatilol 

Relevant academic research and scientific papers

New synthesis of 2,6-diaryl-4-oxo-3,7-dioxabicyclo[3.3.0]octanes: Syntehsis of (±)-styraxin

An efficient method for the stereocontrolled synthesis of the unsymmetrically substituted 4-oxofurofuran lignan 1 has been developed based on a stereocontrolled aldol reaction of the succinic anhydride derivative 20 with an aromatic aldehyde employing(±)-styraxin as a representative example.

A New Synthetic Route to Furofuranoid Lignans via Intramolecular Mukaiyama reaction

The sequence set out in Scheme 1 provides a short and expedient synthesis of a number of (+/-)-furofuranoid lignans, including styraxin 3 (antitumor), aptosimon 5, asarinin 6, pluviatilol 7, 'MEL' 4 (inhibitor of germination) and related compounds.