1056020-06-4Relevant articles and documents
One-pot synthesis of multifunctionalized m-terphenyls
Chang, Meng-Yang,Chan, Chieh-Kai,Lin, Shin-Ying,Wu, Ming-Hao
, p. 9616 - 9624 (2013/10/22)
A facile one-step synthetic protocol toward multifunctionalized m-terphenyls 5 and sulfonyl m-terphenyls 6 is developed from substituted chalcones 1 and allyl sulfone 2 in good yields via a [3C+3C] annulation. The NaH-mediated annulation features transition metal catalyst-free condition. Chalcones 1 with the functional groups tolerance are easily prepared via Claisen-Schmidt condensation of substituted benzaldehydes 3 with acetophenone 4 in a qualitative yield under an aqueous alkaline methanolic solution.