1056247-06-3Relevant academic research and scientific papers
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors
Piatnitski Chekler, Eugene L.,Katoch-Rouse, Reeti,Kiselyov, Alexander S.,Sherman, Dan,Ouyang, Xiaohu,Kim, Ki,Wang, Ying,Hadari, Yaron R.,Doody, Jacqueline F.
, p. 4344 - 4347 (2008)
We have discovered novel inhibitors of VEGFR-2 kinase with low nanomolar potency in both enzymatic and cell-based assays. Active series are heteroaryl-ketone compounds containing a central aromatic ring with either an indazolyl or indolyl keto group in th
