105637-50-1 Usage
Chemical Properties
Crystalline Solid
Uses
Different sources of media describe the Uses of 105637-50-1 differently. You can refer to the following data:
1. Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant
2. Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular relaxant.
Biological Activity
Selective inhibitor of myosin light chain kinase (MLCK). K i values are 32, 4, and 54 μ M for PKA, MLCK, and PKC respectively. Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca 2+ entry (SOCE).
Check Digit Verification of cas no
The CAS Registry Mumber 105637-50-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,6,3 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 105637-50:
(8*1)+(7*0)+(6*5)+(5*6)+(4*3)+(3*7)+(2*5)+(1*0)=111
111 % 10 = 1
So 105637-50-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H17ClN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
