1056632-54-2

Basic information

• Product Name: 1-(4-trifluoromethoxyanilino)-4-phenylthiomethylphthalazine
• Synonyms: 1-(4-trifluoromethoxyanilino)-4-phenylthiomethylphthalazine
• CAS NO: 1056632-54-2
• Molecular Weight: 427.45
• Mol File: 1056632-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-trifluoromethoxyanilino)-4-phenylthiomethylphthalazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-trifluoromethoxyanilino)-4-phenylthiomethylphthalazine(1056632-54-2)
• EPA Substance Registry System: 1-(4-trifluoromethoxyanilino)-4-phenylthiomethylphthalazine(1056632-54-2)

Safety Data

• Hazardous Substances Data: 1056632-54-2(Hazardous Substances Data)

Upstream product

• 7460-55-1 2-(2-bromoacetyl)benzoic acid methyl ester 
• 929613-64-9 1-chloro-4-phenylthiomethylphthalazine 
• 461-82-5 4-(trifluoromethoxy)aniline 
• 1077-79-8 methyl 2-acetylbenzoate 
• 577-56-0 2-acetyl-benzoic acid 
• 85-44-9 phthalic anhydride 
• 929613-62-7 1-hydroxy-4-phenylthiomethylphthalazine 
• 929613-60-5 methyl 2-(2-(phenylthio)acetyl)benzoate 

Relevant articles and documents

Synthesis and anticancer activities of novel 1,4-disubstituted phthalazines

A series of novel 1-anilino-4-(arylsulfanylmethyl)phthalazines were designed and synthesized. The structures of all the compounds were confirmed by IR, 1H-NMR, elemental analysis and MS. The analogues 1-(3-chloro-4-fluoroanilino)-4-(3,4-difluorophenylthio-methyl)phthalazine (12) and 1-(4-fluoro-3-trifluoromethylanilino)-4-(3,4-difluorophenyl-thiomethyl) phthalazine (13) showed higher activity than a cisplatin control when tested in vitro against two different cancer cell lines using the microculture tetrazolium method (MTT) method.