105679-18-3

Basic information

• Product Name: 1H-Indole, 1-benzoyl-4,5,6,7-tetrahydro-
• CAS NO: 105679-18-3
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 105679-18-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-benzoyl-4,5,6,7-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-benzoyl-4,5,6,7-tetrahydro-(105679-18-3)
• EPA Substance Registry System: 1H-Indole, 1-benzoyl-4,5,6,7-tetrahydro-(105679-18-3)

Safety Data

• Hazardous Substances Data: 105679-18-3(Hazardous Substances Data)

Usage

Chemical structure

A synthetic derivative of indole with a benzoyl group attached to a tetrahydroindole moiety.

Occurrence

Heterocyclic aromatic compound found in plants and as a metabolic product of tryptophan in human feces.

Use in research and pharmaceutical development

Utilized in research and pharmaceutical development due to its potential therapeutic properties.

Therapeutic potential

Has been investigated for its role as a serotonin receptor agonist and its potential application in the treatment of various psychiatric and neurological disorders.

Need for further research

Further research is necessary to fully understand its pharmacological effects and potential therapeutic uses.

Upstream product

• 887629-72-3 C₁₅H₁₉NO 
• 1496-76-0 N-benzoylindole 
• 41302-34-5 2-(methoxycarbonyl)cyclohexanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 127441-70-7 β-hydroxyphenethylamino-2 cyclohexene-1 carboxylate d'ethyle 
• 105679-12-7 2-(2-Hydroxy-2-phenyl-ethylamino)-cyclohex-1-enecarboxylic acid methyl ester 

Relevant articles and documents

Solvent free selective dehydrogenation of indolic and carbazolic molecules with an iridium pincer catalyst

A previously known iridium POCOP pincer catalyst was found to selectively dehydrogenate the heterocyclic portion of several indolic and carbazolic molecules. These molecules were found to have an "activity window" (172-178 °C) upon which only the heterocyclic ring underwent dehydrogenation. All reactions were run solvent free, yields for selected substrates were excellent, and the products were isolated by either distillation or alumina plug filtration. the Partner Organisations 2014.

THERMOLYSE COMPAREE D'ENAMINOESTERS CYCLIQUES A CINQ ET SIX CHAINONS : SYNTHESE DE TETRAHYDROINDOLES ET D'OXAZOLES

The thermal behaviour of cyclic enaminoesters 1a-d shows a divergence of chemioselectivity as a function of ring size : six and five ring derivatives lead respectively to tetrahydroindoles (3a,b and 4a,b) and oxazole (5c,d).These results may be rationalized by geometrical constraints during the electrocyclisation of intermediate azomethine ylides 5.