1056901-34-8

Upstream product

• 1056901-33-7 1-(1-tert-butoxycarbonyl-ethyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 192702-01-5 3-chloro-4-fluorobenzyl bromide 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 39149-80-9 tert-butyl 2-bromopropionate 

Downstream Products

• 1056901-35-9 1-[1-carboxy-2-(3-chloro-4-fluoro-phenyl)-1-methyl-ethyl]-1H-pyrrole-2-carboxylic acid methyl ester 
• 1056901-39-3 {3-[5-(3-chloro-4-fluoro-benzyl)-8-hydroxy-5-methyl-6-oxo-5,6-dihydro-indolizin-7-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-carbamic acid tert-butyl ester 
• 1056901-21-3 N-{3-[5-(3-chloro-4-fluoro-benzyl)-8-hydroxy-5-methyl-6-oxo-5,6-dihydro-indolizin-7-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 1056901-40-6 7-(7-amino-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-5-(3-chloro-4-fluoro-benzyl)-8-hydroxy-5-methyl-indolizin-6-one 
• 1056901-37-1 2-[3-(3-chloro-4-fluoro-phenyl)-2-(2-methoxycarbonyl-pyrrol-1-yl)-2-methyl-propionyl]-malonic acid benzyl ester methyl ester 
• 1056901-38-2 1-[1-(3-chloro-4-fluoro-benzyl)-3-methoxycarbonyl-1-methyl-2-oxo-propyl]-1H-pyrrole-2-carboxylic acid methyl ester 
• 1056901-41-7 5-(3-chloro-4-fluoro-benzyl)-8-hydroxy-5-methyl-6-oxo-5,6-dihydro-indolizine-7-carboxylic acid methyl ester 

Relevant academic research and scientific papers

5,5-DISUBSTITUTED-INDOLIZINONE COMPOUNDS

The invention is directed to 5,5-disubstituted-indolizinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.