105694-44-8 Usage
General Description
7-Bromoisobenzofuran-1(3H)-one is a chemical compound with the molecular formula C8H5BrO2. It is a brominated derivative of isobenzofuran-1(3H)-one and is commonly used in the field of organic synthesis as a reagent for various chemical reactions. As a versatile building block, it is employed in the preparation of various pharmaceuticals, agrochemicals, and functional materials. It is known for its ability to undergo a range of chemical transformations, including palladium-catalyzed cross-coupling, nucleophilic aromatic substitution, and Suzuki-Miyaura cross-coupling. 7-Bromoisobenzofuran-1(3H)-one is also used in the production of fluorescent dyes and as a precursor for the synthesis of heterocyclic compounds. Additionally, the presence of a bromine atom in the molecule provides it with unique reactivity, making it valuable in the design and development of new chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 105694-44-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,6,9 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 105694-44:
(8*1)+(7*0)+(6*5)+(5*6)+(4*9)+(3*4)+(2*4)+(1*4)=128
128 % 10 = 8
So 105694-44-8 is a valid CAS Registry Number.
105694-44-8Relevant articles and documents
Synthesis and biological activity of n-butylphthalide derivatives
Wang, Wei,Cha, Xue-Xiang,Reiner, John,Gao, Yuan,Qiao, Hai-Ling,Shen, Jia-Xiang,Chang, Jun-Biao
experimental part, p. 1941 - 1946 (2010/06/19)
A series of n-butylphthalide derivatives were designed and synthesized. The in vitro activities of these compounds were evaluated by a resting tension of isolated rat thoracic aorta ring assay. Compounds 4g and 4i were found to be more active than n-butylphthalide.
17O NUCLEAR MAGNETIC RESONANCE SPECTROSCOPIC STUDY OF SUBSTITUTED PHTHALIC ANHYDRIDES AND PHTHALIDES
Boykin, David W.,Baumstark, Alfons L.,Kayser, Margaret M.,Soucy, Chantal M.
, p. 1214 - 1217 (2007/10/02)
17O chemical shift data (natural abundance) for 3-substituted phthalic anhydrides and 4- and 7-substituted phthalides in acetonitrile at 75 deg C are reported.Steric interactions of substituents ortho to the carbonyl groups result in deshielding effects (9-22 ppm) relative to parent compounds regardless of the electronic character of the substituents.Factors contributing to the deshielding effects are discussed.The relationship between 17O chemical shifts and regiochemistry of the phthalic anhydrides is discussed.
