1056968-18-3

Basic information

• Product Name: (S)-N-(1-oxopentyl)-N-[[2'-[(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-valine
• Synonyms: (S)-N-(1-oxopentyl)-N-[[2'-[(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-valine
• CAS NO: 1056968-18-3
• Molecular Weight: 553.704
• Mol File: 1056968-18-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-(1-oxopentyl)-N-[[2'-[(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-valine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(1-oxopentyl)-N-[[2'-[(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-valine(1056968-18-3)
• EPA Substance Registry System: (S)-N-(1-oxopentyl)-N-[[2'-[(1-methyl-1-phenyl-ethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-valine(1056968-18-3)

Safety Data

• Hazardous Substances Data: 1056968-18-3(Hazardous Substances Data)

Upstream product

• 1080555-70-9 C₃₃H₃₇N₅O₃ 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF VALSARTAN

The present invention relates to a process for preparing valsartan from a compound of general formula (I), wherein R is cumyl, trityl or t-butyl. The process comprises a first step, wherein the protective group is eliminated and thereafter the oxazolidinone ring is opened by catalytic hydrogenationin the presence of an organic base. Finally, Valsartanor a pharmaceutically acceptable salt thereofis isolated.