105707-06-0Relevant academic research and scientific papers
Microwave-mediated domino reactions in dry medium. Preparation of dihydropyridinones and pyridinones structurally related to Hantzsch esters
Eynde, Jean Jacques Vanden,Labuche, Nadège,Van Haverbeke, Yves
, p. 3683 - 3690 (2007/10/03)
Microwave irradiation of mixtures of 4-arylmethylene-2-phenyloxazol-5(4H)-ones and enaminocarbonyl compounds, in the absence of solvent, affords dihydropyridinone derivatives in quantitative yields. From 4-ethoxymethylene-2-phenyloxazol-5(4H)one and enami
ETUDE DE LA REACTIVITE D'YLIDENEOXAZOLINE-5-ONES VIS-A-VIS DE COMPOSES ENAMINOCARBONYLES.
Maquestiau, A.,Vanden Eynde, J.-J.,Papleux, P.
, p. 849 - 858 (2007/10/02)
Reactions between 4-ylideneoxazolin-5-ones and enaminocarbonyl compounds do not lead to 4,7-dihydrooxazolopyridines.These reactions yield, by cleavage of the five-membered ring, monocyclic derivatives whose structures are elucidated.Thus, starting from 4-arylideneoxazolin-5-ones, mixtures of cis and trans dihydro-α-pyridones are formed but, in most cases, only the cis isomers can be isolated.Starting from 2-phenyl-4-ethoxymethyleneoxazolin-5-one, reactions proceed, in addition, by loss of ethanol and α-pyridones are obtained.
