1057407-36-9Relevant articles and documents
[(3-Cyanopropyl)diisopropylsilyl] acetylene, a more stable analogue of [(3-Cyanopropyl)dimethylsilyl]acetylene
Gaefke, Gerald,Hoeger, Sigurd
experimental part, p. 2155 - 2157 (2009/04/04)
The preparation and application of a new alkyne protecting group is presented. The reactivity and stability of [(3-cyanopropyl)diisopropylsilyl] acetylene is similar to that of the well-known (triisopropylsilyl)acetylene. Its high polarity simplifies chromatographic separation after coupling to aromatics with more than one reactive site. Moreover, compounds with more than one [(3-cyanopropyl)diisopropylsilyl]acetylene group are easily purified after partial deprotection. Georg Thieme Verlag Stuttgart.