105746-15-4

Basic information

• Product Name: Phenol, 4-(4-propyl-1-piperazinyl)-
• CAS NO: 105746-15-4
• Molecular Formula: C13H20N2O
• Molecular Weight: 220.315
• Mol File: 105746-15-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(4-propyl-1-piperazinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(4-propyl-1-piperazinyl)-(105746-15-4)
• EPA Substance Registry System: Phenol, 4-(4-propyl-1-piperazinyl)-(105746-15-4)

Safety Data

• Hazardous Substances Data: 105746-15-4(Hazardous Substances Data)

Upstream product

• 38212-30-5 4-(4-methoxyphenyl)piperazine 
• 621-68-1 bis(2-chloroethyl)propylamine 
• 123-30-8 4-amino-phenol 

Downstream Products

• 90863-19-7 4-Nitro-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 
• 90863-17-5 1-n-Propyl-4-<4-(4-brom-benzoyloxy)-phenyl>-piperazin 
• 90863-13-1 4-Hexyl-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 
• 105780-74-3 4-Nonyloxy-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 
• 90863-15-3 4-Butoxy-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 
• 1369589-05-8 4-(4-propylpiperazin-1-yl)phenyl trifluoromethanesulfonate 
• 90863-16-4 1-n-Propyl-4-<4-(4-chlor-benzoyloxy)-phenyl>-piperazin 
• 90863-18-6 1-n-Propyl-4-<4-(4-trifluor-methyl-benzoyloxy)-phenyl>-piperazin 
• 90863-20-0 4-Cyano-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 
• 105745-91-3 4-Fluoro-benzoic acid 4-(4-propyl-piperazin-1-yl)-phenyl ester 

Relevant articles and documents

Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors

A series of para-substituted 4-phenylpiperidines/piperazines have been synthesized and their affinity to recombinant rat cerebral cortex monoamine oxidases A (MAO A) and B (MAO B) determined. Para-substituents with low dipole moment increased the affinity to MAO A, whereas groups with high dipole moment yielded compounds with no or weak affinity. In contrast, the properties affecting MAO B affinity were the polarity and bulk of the para-substituent, with large hydrophobic substituents producing compounds with high MAO B affinity. In addition, these compounds were tested in freely moving rats and the effect on the post-mortem neurochemistry was measured. A linear correlation was demonstrated between the affinity for MAO A, but not MAO B, and the levels of 3,4-dihydroxyphenylacetic acid (DOPAC) and 3-methoxytyramine (3-MT) in the striatum.

Liquid-crystalline Heterocycloalkanes. II. Syntheses and Liquid-crystalline Properties of Substituted 1-Phenylpiperazines

Several homologous series of the 1,4-disubstituted piperazines of the general formulas 4a-l, 6a-k, 7a, b, 8a-r were synthesized.Most of the new substances are liquid crystalline.Besides nematic phases also smectic phases of the types A, B and E exist, which was proved by texture and miscibility studies.