105761-77-1

Basic information

• Product Name: (1R,2S,3R,4S)-(3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methanol
• Synonyms: (1R,2S,3R,4S)-(3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methanol
• CAS NO: 105761-77-1
• Molecular Weight: 156.181
• Mol File: 105761-77-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,2S,3R,4S)-(3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,4S)-(3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methanol(105761-77-1)
• EPA Substance Registry System: (1R,2S,3R,4S)-(3-hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methanol(105761-77-1)

Safety Data

• Hazardous Substances Data: 105761-77-1(Hazardous Substances Data)

Upstream product

• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 

Relevant articles and documents

Synthesis of a functionalized oxabicyclo[2.2.1]-heptene-based chemical library

The 7-oxabicyclo[2.2.1]heptene ring system is a common structural motif in many pharmacologically interesting molecules. We recognized the potential to employ this highly oxygenated and conformationally-restricted scaffold in diversity-oriented synthesis to generate a library of non-chiral but topologically complex compounds. Herein, we report the synthesis and biological evaluation of two 96-member tricyclic libraries containing the oxabicyclo[2.2.1]heptene framework using acetal formation as the key step.